Oral prebiotics: an alternative for treatment and prevention of caries

Authors

DOI:

https://doi.org/10.22201/cuaieed.16076079e.2023.24.4.1

Keywords:

caries, prebiotics, oral health, remineralization

Abstract

Caries is the most common oral disease worldwide; it is caused by excessive acid production, which is formed when bacteria that colonize the mouth digest the sugars present in diet. However, there are sugars that oral bacteria cannot digest that are known as prebiotics. Prebiotics are compounds that can be selectively used by host microorganisms, especially from the intestine, that confer a health benefit on them. They are found naturally in foods such as milk, honey, vegetables, greens, fruits, cereals, legumes, and nuts; they can also be obtained by chemical or enzymatic synthesis. New therapeutic and preventive approaches to caries have emerged, focused on prebiotics in oral hygiene products, foods, and supplements; however, its use is not a common practice in dentistry. It is important to know more about the benefit that prebiotics offer to the oral health of individuals, to promote their routine use as a complement to dental treatments performed.

Author Biographies

Juan Gerardo Sánchez Medina, Universidad Autónoma de San Luis Potosí

Médico Estomatólogo egresado de la Universidad Autónoma de San Luis Potosí (uaslp). Cuenta con maestría en Ciencias Biomédicas Básicas por la Facultad de Medicina de la uaslp. Técnico Académico del Laboratorio de Bioquímica, Microbiología y Patología Oral de la Facultad de Estomatología de la uaslp.

Saray Aranda Romo, Universidad Autónoma de San Luis Potosí

Egresada de la Facultad de Estomatología de la UASLP, con especialidad en patología bucal y medicina bucal. Cuenta con maestría y doctorado en Ciencias Biomédicas Básicas. Es miembro del Sistema Nacional de Investigadores (SNI), profesora investigadora de tiempo completo y coordinadora de la Clínica de diagnóstico de la Facultad de Estomatología de la UASLP.

Rita Elizabeth Martínez Martínez, Universidad Autónoma de San Luis Potosí

Egresada de la Facultad de Estomatología de la Universidad Autónoma de San Luis Potosí (uaslp), maestría en Ciencias Odontológicas en el área de Odontología Integral Avanzada, uaslp. Doctorado en Ciencias Biomédicas Básicas. Miembro del Sistema Nacional de Investigadores (sni), nivel II. Profesora investigadora de tiempo completo de la Facultad de Estomatología de la uaslp.

Mauricio Comas García, Universidad Autónoma de San Luis Potosí

Licenciado en Química por la Universidad Autónoma de San Luis Potosí (uaslp), cuenta con Doctorado en Química por la University of California. Actualmente, forma parte del Sistema Nacional de Investigadores (sni), nivel I. Profesor-Investigador de Tiempo Completo de la Facultad de Ciencias. Centro de Investigación en Ciencias de la Salud y Biomedicina de la uaslp.

Othoniel Hugo Aragón Martínez, Universidad Autónoma de San Luis Potosí

Químico Farmacobiólogo, cuenta con Maestría y Doctorado en Ciencias Biomédicas Básicas. Está a cargo del Departamento de Farmacología de la Facultad de Medicina de la UASLP. Actualmente, forma parte del SNI. Profesor asociado en el Posgrado en Ciencias Biomédicas Básicas de la Facultad de Medicina, UASLP.

References

Bijle, M. N. A., Ekambaram, M., Lo, E. C. M., y Yiu, C. K. Y. (2019). The combined antimicrobial effect of arginine and fluoride toothpaste. Scientific reports, 9, 8405. https://doi.org/10.1038/s41598-019-44612-6.

Davani-Davari, D., Negahdaripour, M., Karimzadeh, I., Seifan, M., Mohkam, M., Masoumi, S. J., Berenjian, A., y Ghasemi, Y. (2019). Prebiotics: Definition, Types, Sources, Mechanisms, and Clinical Applications. Foods, 8(3), 92. https://doi.org/10.3390/foods8030092.

Janakiram, C., Deepan Kumar, C. V., y Joseph, J. (2017). Xylitol in preventing dental caries: A systematic review and meta-analyses. Journal of natural science, biology, and medicine, 8(1), 16-21. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320817/.

Keijser, B. J. F., van den Broek, T. J., Slot, D. E., van Twillert, L., Kool, J., Thabuis, C., Ossendrijver, M., van der Weijden, F. A., y Montijn, R. C. (2018). The Impact of Maltitol-Sweetened Chewing Gum on the Dental Plaque Biofilm Microbiota Composition. Frontiers in microbiology, 9, 381. https://doi.org/10.3389/fmicb.2018.00381.

Lamont, R. J., Koo, H., y Hajishengallis, G. (2018). The oral microbiota: dynamic communities and host interactions. Nature reviews. Microbiology, 16(12), 745-759. https://doi.org/10.1038/s41579-018-0089-x.

Lin, T. H., Lin, C. H., y Pan, T. M. (2018). The implication of probiotics in the prevention of dental caries. Applied microbiology and biotechnology, 102(2), 577-586. https://doi.org/10.1007/s00253-017-8664-z.

López-López, A., Camelo-Castillo, A., Ferrer, M. D., Simon-Soro, Á., y Mira, A. (2017). Health-Associated Niche Inhabitants as Oral Probiotics: The Case of Streptococcus dentisani. Frontiers in microbiology, 8, 379. https://doi.org/10.3389/fmicb.2017.00379.

Nascimento M. M. (2018). Potential Uses of Arginine in Dentistry. Advances in dental research, 29(1), 98-103. https://doi.org/10.1177/0022034517735294.

Nunpan, S., Suwannachart, C., y Wayakanon, K. (2019). Effect of Prebiotics-Enhanced Probiotics on the Growth of Streptococcus mutans. International journal of microbiology, 2019, 4623807. https://doi.org/10.1155/2019/4623807.

Rosier, B. T., Buetas, E., Moya-Gonzalvez, E. M., Artacho, A., y Mira, A. (2020). Nitrate as a potential prebiotic for the oral microbiome. Scientific reports, 10(1), 12895. https://doi.org/10.1038/s41598-020-69931-x.

Salli, K., Lehtinen, M. J., Tiihonen, K., y Ouwehand, A. C. (2019). Xylitol’s Health Benefits beyond Dental Health: A Comprehensive Review. Nutrients, 11(8), 1813. https://doi.org/10.3390/nu11081813.

Secretaría de Salud.gob.mx. (2022). Resultados del Sistema de Vigilancia Epidemiológica de Patologías Bucales sivepab 2020. https://www.gob.mx/cms/uploads/attachment/file/765740/resultadosSIVEPAB_2020.pdf.

Takeuchi, K., Asakawa, M., Hashiba, T., Takeshita, T., Saeki, Y., y Yamashita, Y. (2018). Effects of xylitol-containing chewing gum on the oral microbiota. Journal of oral science, 60(4), 588-594. https://doi.org/10.2334/josnusd.17-0446.

Vanhatalo, A., Blackwell, J. R., L’Heureux, J. E., Williams, D. W., Smith, A., van der Giezen, M., Winyard, P. G., Kelly, J., y Jones, A. M. (2018). Nitrate-responsive oral microbiome modulates nitric oxide homeostasis and blood pressure in humans. Free radical biology & medicine, 124, 21-30. https://doi.org/10.1016/j.freeradbiomed.2018.05.078.

Zaura, E., y Twetman, S. (2019). Critical Appraisal of Oral Pre- and Probiotics for Caries Prevention and Care. Caries research, 53(5), 514-526. https://doi.org/10.1159/000499037.

Zhang, J. S., Chu, C. H., y Yu, O. Y. (2022). Oral Microbiome and Dental Caries Development. Dentistry journal, 10(10), 184. https://doi.org/10.3390/dj10100184.

Published

2023-06-28

Issue

Vol. 24 No. 4 (2023): Darnos una nueva vida

Section

Varietas

License

Copyright (c) 2023 Revista Digital Universitaria

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Licencia Creative Commons
Revista Digital Universitaria es editada por la Universidad Nacional Autónoma de México se distribuye bajo una Licencia Creative Commons Atribución-NoComercial 4.0 Internacional. Basada en una obra en http://revista.unam.mx/.

Most read articles by the same author(s)